New combo therapy aims to strengthen esophagus in tough reflux cases

NCT ID NCT07174882

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tests whether adding a treatment to strengthen the esophagus lining can improve symptoms for people with non-erosive reflux disease (NERD), a common form of GERD that doesn't show visible damage. About 60 adults with NERD will receive a combination of standard acid-reducing medication and a therapy to boost the barrier function of the esophagus. The goal is to see if this approach reduces symptoms like heartburn and improves the health of the esophageal tissue.

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Contacts and locations

Locations

  • V.Kh.Vasilenko Clinic of Propedeutics of Internal Diseases, Gastroenterology and Hepatology, I.M.Sechenov First Moscow State Medical University (Sechenov University). Gastroenterology department, outpatient clinic.

    Moscow, 119991, Russia

Conditions

Explore the condition pages connected to this study.