New drug duo may help new moms avoid a second needle for headache relief

NCT ID NCT05116930

First seen Mar 26, 2026 · Last updated May 13, 2026 · Updated 7 times

Summary

This study tests whether a combination of two drugs, neostigmine and glycopyrrolate, can treat severe headaches that sometimes happen after an epidural is placed for labor pain relief. The goal is to see if this treatment can reduce the number of new mothers who need a procedure called an epidural blood patch to stop the headache. The study involves 18 postpartum women who developed a headache within 72 hours of delivery.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.