Bladder cancer breakthrough? new combo aims to shrink tumors before surgery

NCT ID NCT07414992

First seen Feb 25, 2026 · Last updated May 06, 2026 · Updated 6 times

Summary

This study is for people with muscle-invasive bladder cancer who cannot or choose not to receive standard chemotherapy. It tests whether giving focused radiation (SBRT) along with immunotherapy drugs (cemiplimab with or without fianlimab) before bladder removal surgery can safely shrink or eliminate the cancer. About 44 participants will receive the treatment and then have surgery to see how well the cancer responded.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.