Immunotherapy combo shows promise in shrinking Early-Stage melanoma before surgery

NCT ID NCT05418972

First seen Nov 19, 2025 · Last updated May 14, 2026 · Updated 21 times

Summary

This study tests whether giving two immunotherapy drugs (relatlimab and nivolumab) before surgery can shrink tumors in people with high-risk stage II melanoma. About 20 participants will receive two doses of the drugs, then have surgery to remove any remaining cancer. The goal is to see how many patients have a complete or near-complete response, meaning little or no tumor left at surgery.

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Contacts and locations

Locations

  • Melanoma Institute Australia

    Wollstonecraft, New South Wales, 2065, Australia

Conditions

Explore the condition pages connected to this study.