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New drug targets mysterious chronic itch

NCT ID NCT07074977

Recruiting now Symptom relief Sponsor: Galderma R&D Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 study tests a drug called nemolizumab in 50 adults with chronic itching that has no known cause. The goal is to see how the drug works in the body and whether it can reduce itching over 16 weeks. Participants receive either nemolizumab or a placebo injection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nemolizumab
What this could lead to
If successful, this could point toward a new treatment option for people with chronic itching that has no clear cause.
What could go wrong
This is an early Phase 2 study with only 50 participants, so results may not apply to everyone. The drug may not reduce itching significantly, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PRURITUS OF UNKNOWN ORIGIN

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Galderma Investigational (Site # 7131)

    NOT_YET_RECRUITING

    Spartanburg, South Carolina, 29307, United States

  • Galderma Investigational (Site# 7048)

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21201, United States

  • Galderma Investigational Site (#7129)

    RECRUITING

    Bowling Green, Kentucky, 42104, United States

  • Galderma Investigational Site (#7130)

    RECRUITING

    The Bronx, New York, 10455, United States

  • Galderma Investigational Site (#8212)

    RECRUITING

    Portland, Oregon, 97210, United States

  • Galderma Investigational Site (#8255)

    RECRUITING

    Philadelphia, Pennsylvania, 19103, United States

  • Galderma Investigational Site (#8295)

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

  • Galderma Investigational Site (#8768)

    NOT_YET_RECRUITING

    Tucson, Arizona, 85718, United States

  • Galderma Investigational Site (#9975)

    RECRUITING

    Sacramento, California, 95815, United States

  • Galderma Investigational Site (site# 7054)

    RECRUITING

    Tampa, Florida, 33609, United States

  • Galderma Investigational Site (site# 7075)

    RECRUITING

    San Francisco, California, 94115, United States

  • Galderma Investigational Site (site# 7110)

    RECRUITING

    New City, New York, 10956, United States

  • Galderma Investigational Site (site# 7111)

    RECRUITING

    Fargo, North Dakota, 58103, United States

  • Galderma Investigational Site (site# 8003)

    RECRUITING

    Webster, Texas, 77598, United States

  • Galderma Investigational Site (site# 8021)

    NOT_YET_RECRUITING

    San Diego, California, 92123, United States

  • Galderma Investigational Site (site# 8045)

    NOT_YET_RECRUITING

    Québec, Quebec, G1V 4X7, Canada

  • Galderma Investigational Site (site# 8108)

    RECRUITING

    Las Vegas, Nevada, 89145, United States

  • Galderma Investigational Site (site# 8130)

    RECRUITING

    Los Angeles, California, 90045, United States

  • Galderma Investigational Site (site# 8142)

    NOT_YET_RECRUITING

    Indianapolis, Indiana, 46250, United States

  • Galderma Investigational Site (site# 8521)

    NOT_YET_RECRUITING

    Saint Joseph, Missouri, 64506, United States

  • Galderma Investigational Site (site# 8608)

    NOT_YET_RECRUITING

    Santa Monica, California, 90404, United States

  • Galderma Investigational Site (site# 8636)

    RECRUITING

    Fountain Valley, California, 92708, United States

  • Galderma Investigational Site (site# 8725)

    RECRUITING

    Morgantown, West Virginia, 26505, United States

  • Galderma Investigational Site (site# 8743)

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Galderma Investigational Site (site# 8862)

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Galderma Investigational Site (site# 8893)

    RECRUITING

    Birmingham, Alabama, 35244, United States

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