New hope for kids with rare kidney disease

NCT ID NCT05001269

Summary

This study tested a drug called nedosiran in children from birth to 11 years old who have primary hyperoxaluria, a rare genetic disease that causes kidney stones and can lead to kidney failure. The main goal was to see if the monthly treatment safely lowers the harmful oxalate levels in the children's urine and helps protect their kidney function. Researchers also closely monitored the drug's safety and how it works in the body of these young patients.

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Contacts and locations

Locations

  • Clinical Research Site

    Rochester, Minnesota, 55905, United States

  • Clinical Research Site

    Hamilton, Ontario, L8S 4K1, Canada

  • Clinical Research Site

    Heidelberg, 69120, Germany

  • Clinical Research Site

    Fukuoka, 830-0011, Japan

  • Clinical Research Site

    Nagoya, 467-8602, Japan

  • Clinical Research Site

    Beirut, 1100, Lebanon

  • Clinical Research Site

    Bialystok, 15-274, Poland

  • Clinical Research Site

    Barcelona, 08035, Spain

  • Clinical Research Site

    Yenimahalle, Ankara, 06506, Turkey (Türkiye)

  • Clinical Trial Site

    Bonn, 53127, Germany

  • Clinical Trial Site

    Roma, 00165, Italy

  • Clinical Trial Site

    Dubai, +971, United Arab Emirates

  • Clinical Trial Site

    London, WC1N 3JH, United Kingdom

Conditions

Explore the condition pages connected to this study.