New imaging agent could sharpen bladder cancer detection

NCT ID NCT05321316

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new radioactive tracer called 68Ga-N188 that targets a protein called nectin-4, often found on urothelial cancer cells. Researchers will use PET/CT scans to see how well this tracer spots tumors in 20 people with recurrent or advanced bladder cancer. The goal is to improve imaging for better diagnosis and monitoring of the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

68Ga-N188 (a radioactive tracer for PET imaging)

What this could lead to

If successful, this could provide a more accurate way to detect and monitor urothelial carcinoma, especially in recurrent or advanced cases, potentially guiding better treatment decisions.

What could go wrong

This is a small, early-phase imaging study with only 20 participants, so results may not apply broadly. The probe's ability to improve patient outcomes over standard imaging is not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Email: •••••@•••••