First human test of new drug for tough blood cancers halted early

NCT ID NCT05787496

Summary

This early-stage study tested a new drug called NC525 in adults with advanced blood cancers that had returned or stopped responding to standard treatments. The main goal was to check the drug's safety and side effects in 28 participants. The study was terminated early, and while it also looked for signs of effectiveness, its primary focus was on determining safe dosage levels.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • City of Hope

    Duarte, California, 91010, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • Washington University School of Medicine in St. Louis

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medicine

    New York, New York, 10022, United States

Conditions

Explore the condition pages connected to this study.