New combo therapy targets esophageal cancer with Radiation-Activated nanoparticles

NCT ID NCT04615013

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 22 times

Summary

This early-phase study tests a new drug called NBTXR3, which is activated by radiation, along with standard chemotherapy for people with esophageal adenocarcinoma. The goal is to find the safest dose and see if this combination can better control the disease. About 24 adults with stage II or III esophageal cancer will receive the drug injected into their tumor, followed by radiation and chemo.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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