New hope for tough lymphomas? early trial of NB02 begins

NCT ID NCT07114367

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing a new drug called NB02 (posseltinib) in 9 adults with certain types of Non-Hodgkin lymphoma (follicular, mantle cell, or marginal zone) that have returned or not responded to at least two prior treatments. The main goals are to find a safe dose and check for side effects, while also looking for signs that the drug might fight the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NB02 (posseltinib)

What this could lead to

If this works, it could point toward a new treatment option for people with certain types of Non-Hodgkin lymphoma that have not responded to other therapies.

What could go wrong

This is a very early, small Phase 1 trial with only 9 participants, so it is mainly checking safety and dosing. It is too soon to know if the drug will effectively shrink tumors or help patients feel better.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MANTLE CELL LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

follicular lymphoma lymphoma mantle cell lymphoma marginal zone lymphoma non-Hodgkin lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Catholic univ of Yeouido St Mary's Hospital

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chonnam National University Hwasun Hospital

    RECRUITING

    Hwasun, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Samsung Medical Center

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Bundang Hospital

    RECRUITING

    Seongnam, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Hospital

    RECRUITING

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ulsan University Hospital

    RECRUITING

    Ulsan, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••