Simple nose spray may keep kids breathing easy during surgery

NCT ID NCT07000877

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nasal decongestant spray given before anesthesia can reduce breathing complications in children aged 1 to 8 who have a cold and need surgery. Two hundred children will receive either the active spray or a placebo, and doctors will monitor for issues like coughing, airway blockage, or low oxygen. The goal is to find a simple, low-risk way to make anesthesia safer for kids with upper respiratory infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxymetazoline hydrochloride (0.05%) nasal spray

What this could lead to

If it works, this simple nasal spray could become a standard way to reduce breathing problems in children with colds who need surgery.

What could go wrong

This is a small, early-phase trial, so results may not apply to all children. The spray might not reduce complications significantly compared to a placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Perth Children's Hospital

    RECRUITING

    Perth, We, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••