Simple nose spray may keep kids breathing easy during surgery

NCT ID NCT07000877

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a nasal decongestant spray given before anesthesia can reduce breathing complications in children aged 1 to 8 who have a cold and need surgery. Two hundred children will receive either the active spray or a placebo, and doctors will monitor for issues like coughing, airway blockage, or low oxygen. The goal is to find a simple, low-risk way to make anesthesia safer for kids with upper respiratory infections.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
oxymetazoline hydrochloride (0.05%) nasal spray
What this could lead to
If it works, this simple nasal spray could become a standard way to reduce breathing problems in children with colds who need surgery.
What could go wrong
This is a small, early-phase trial, so results may not apply to all children. The spray might not reduce complications significantly compared to a placebo.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Perth Children's Hospital

    RECRUITING

    Perth, We, Australia

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