Stem cell nasal spray takes on sinusitis
NCT ID NCT07635459
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new nasal spray for adults with chronic sinusitis. The spray turns into a gel inside the nose and releases three active ingredients: stem cell exosomes to help repair the nasal lining, an antihistamine to reduce inflammation, and an antiviral agent. The goal is to see if it is safe and can ease symptoms during a flare-up. 108 participants will be randomly assigned to receive the full spray, a version without exosomes, or a placebo gel.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
a gel nasal spray containing stem cell exosomes, azelastine (antihistamine), and interferon alpha-2b (antiviral)
What this could lead to
If it works, this spray could offer a new way to manage chronic sinusitis flare-ups by reducing inflammation and fighting viruses.
What could go wrong
This is a very early (Phase 1) study focused on safety, not effectiveness. The spray is complex and may cause side effects like irritation or taste changes. Success is far from guaranteed.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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