Needle-Free apomorphine: nasal spray safety trial begins
NCT ID NCT06954428
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new nasal spray form of apomorphine (NT-301) in 49 healthy adults to see if it is safe and how the body processes it. Participants received either the nasal spray or a placebo, and some also received an apomorphine injection for comparison. The goal was to gather early safety and drug-level information, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
apomorphine nasal spray (NT-301)
What this could lead to
If successful, this could lead to a needle-free way to deliver apomorphine, potentially improving convenience for people who need it.
What could go wrong
This is an early Phase 1 study in only 49 healthy volunteers, so it does not test effectiveness for any disease. The nasal spray may not work as well as the injection, and side effects are still being evaluated.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CMAX
Adelaide, South Australia, Australia
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CMAX Clinical Research Center Pty Limited
Adelaide, South Australia, 5000, Australia