Tiny nose swabs could unlock clues to autoimmune relapse
NCT ID NCT03919435
First seen Nov 19, 2025 · Last updated Apr 30, 2026 · Updated 22 times
Summary
This study looks at how the antibiotic trimethoprim-sulfamethoxazole changes the bacteria and fungi living in the noses of people with granulomatosis with polyangiitis (GPA), a rare autoimmune disease. Researchers want to understand if the drug's benefits come from killing germs or from reducing inflammation. About 8 adults with GPA who are in remission will provide nasal swabs and optional blood samples over 6 months.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania, 19104, United States
Conditions
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