Nasal spray could slow brain inflammation in progressive MS
NCT ID NCT06292923
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times
Summary
This study tests a nasal spray called foralumab in people with non-active secondary progressive multiple sclerosis (SPMS), a form of MS that worsens over time. The goal is to see if the drug is safe and can reduce brain inflammation measured by special scans. About 54 adults aged 18-75 will receive either a low dose, high dose, or placebo spray daily for 3 months.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Cornell Weill Medical Center
RECRUITINGNew York, New York, 10021, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Thomas Jefferson University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Buffalo
RECRUITINGBuffalo, New York, 14202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Massachusetts
RECRUITINGWorcester, Massachusetts, 01655, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale
RECRUITINGNorth Haven, Connecticut, 06473, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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