Nose cartilage used to fix knees in new trial

NCT ID NCT06163573

First seen Mar 24, 2026 · Last updated Jun 23, 2026 · Updated 14 times

Summary

This Phase II trial tests whether an implant made from a patient's own nasal cartilage can repair knee damage from patellofemoral osteoarthritis. 75 adults aged 18–65 with moderate knee pain will receive either the cartilage implant or standard platelet-rich plasma injections. The main goal is to see if the implant improves knee pain and function over two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Crossklinik

    RECRUITING

    Basel, 4054, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpitaux universitaires de Genève

    RECRUITING

    Geneva, 1205, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orthopädische Klinik König-Ludwig-Haus

    NOT_YET_RECRUITING

    Würzburg, 97074, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Regionale di Lugano

    RECRUITING

    Lugano, 6962, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Poliklinika Ivković

    RECRUITING

    Zagreb, 10000, Croatia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Poliklinika Ortho Plus

    RECRUITING

    Zagreb, 10000, Croatia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sportclinic, Klinik Hirslanden

    RECRUITING

    Zurich, 8032, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Basel

    RECRUITING

    Basel, 4031, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Freiburg

    NOT_YET_RECRUITING

    Freiburg im Breisgau, 79106, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nasal cartilage graft (N-TEC) or platelet-rich plasma (PRP) injections

What this could lead to

If successful, this could offer a new way to repair knee cartilage and reduce pain from osteoarthritis, potentially delaying or avoiding joint replacement.

What could go wrong

This is an early Phase II trial with only 75 participants, so results may not apply to everyone. The procedure is surgical and carries risks like infection or graft failure.

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.