New hope for bile duct cancer: drug combo shows promise in Late-Stage trial

NCT ID NCT04005339

First seen Jan 29, 2026 · Last updated Apr 30, 2026 · Updated 18 times

Summary

This study tests a combination of three chemotherapy drugs (fluorouracil, leucovorin, and nanoliposomal irinotecan) in people with advanced biliary tract cancer that has worsened after standard treatment. The goal is to see if this new mix can stop the cancer from growing for at least 4 months. The trial involves 48 adults whose cancer has spread or cannot be removed by surgery.

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Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10128, United States

  • Indiana University Health Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Lombardi Comprehensive Cancer Center, Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Washington University School of Medicine- Siteman Cancer Center

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.