New hope for kids with tough-to-treat nerve cancer: three-drug combo tested
NCT ID NCT07261241
First seen Dec 04, 2025 · Last updated May 15, 2026 · Updated 20 times
Summary
This study tests three different combinations of a radioactive drug (131I-MIBG) with other medicines (vorinostat and/or dinutuximab) in children and young adults with neuroblastoma that has come back or not responded to treatment. About 118 participants will be randomly assigned to one of three treatment arms and receive one course of therapy, with an option for a second course if they are healthy enough. The goal is to find which combination shrinks tumors best and to check for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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C.S Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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Children Hospital of Colorado
Aurora, Colorado, 80045, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027-0700, United States
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Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, 98105, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104-4318, United States
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Children's Memorial Hospital - Chicago
Chicago, Illinois, 60614, United States
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Childrens Hospital Boston, Dana-Farber Cancer Institute.
Boston, Massachusetts, 02115, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3039, United States
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Cook Children's Medical Center - Fort Worth
Fort Worth, Texas, 76104, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
Contact Email: •••••@•••••
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UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California, 94143, United States
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University of Texas Southwestern
Dallas, Texas, 75235, United States
Contact Email: •••••@•••••
Conditions
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