Nanotech patch aims to slash opioid use after wisdom tooth surgery
NCT ID NCT07461506
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new nanotechnology patch, called NeuroCuple, placed on the skin for two days after wisdom tooth extraction. The goal is to see if it reduces pain and the need for opioid painkillers. 120 healthy adults aged 18–50 will be randomly assigned to get either the active patch or a sham patch. The main measure is how much opioid medication they use in the first 48 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NeuroCuple patch (a non-drug device using nanotechnology)
What this could lead to
If it works, this could offer a drug-free way to manage dental pain and lower the risk of opioid addiction after wisdom tooth extraction.
What could go wrong
This is an early feasibility study with only 120 people. The patch may not work better than a placebo, and results may not apply to other types of surgery.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Pittsburgh School of Dental Medicine
Pittsburgh, Pennsylvania, 15261, United States
Contact