New naloxone nasal spray put to the test in healthy volunteers
NCT ID NCT05377255
First seen Apr 24, 2026 · Last updated May 12, 2026 · Updated 1 time
Summary
This study tested a new device (AP003) that delivers naloxone as a nasal spray to reverse opioid overdoses. Twenty-four healthy adults received multiple doses to see how the drug moves through the body and to check for side effects. The goal was to compare the new spray with the standard Narcan spray. This early-phase trial focused on safety and drug levels, not on treating an overdose directly.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Syneos Health Clinical Research Services
Miami, Florida, 33136, United States
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