Could a common cough medicine protect the heart during a heart attack?
NCT ID NCT06850831
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving N-Acetylcysteine (NAC), a drug often used for coughs, directly into the heart arteries during emergency angioplasty can reduce damage caused by restoring blood flow. Researchers measured markers of stress, inflammation, and cell death in 70 heart attack patients. The goal is to see if this approach can limit heart muscle injury and improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-Acetylcysteine (NAC)
- What this could lead to
- If it works, this could point toward a simple, low-cost way to limit heart muscle damage during emergency angioplasty after a heart attack.
- What could go wrong
- This is a small Phase 2 trial with only 70 participants, so results may not apply to everyone. The benefit of NAC given this way is unproven, and the study focuses on lab markers, not long-term outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dr. Moewardi General Hospital
Surakarta, Central of Java, 57126, Indonesia
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