Experimental drug shows promise for rare childhood movement disorder

NCT ID NCT03759678

First seen Mar 28, 2026 · Last updated May 15, 2026 · Updated 7 times

Summary

This study tested a drug called N-Acetyl-L-Leucine in 17 people with Ataxia-Telangiectasia (A-T), a rare genetic disease that causes severe movement problems. The goal was to see if the drug could safely improve symptoms like coordination and walking. The study was stopped early, but researchers looked at changes in movement ability over 6 weeks of treatment compared to a period without treatment.

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Contacts and locations

Locations

  • Hospital Universitario La Paz

    Madrid, Spain, Spain

  • Royal Papworth Hospital NHS Foundation Trust

    Cambridge, Cambridgeshire, CB2 0AY, United Kingdom

  • University of California - Los Angeles

    Los Angeles, California, 90095, United States

  • University of Giessen

    Giessen, Germany

Conditions

Explore the condition pages connected to this study.