New drug cocktail aims to outsmart resistant lung cancer

NCT ID NCT06745908

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This phase 3 trial tests whether adding an experimental drug (N-803) to standard chemotherapy (docetaxel) can help people with advanced non-small cell lung cancer whose disease has stopped responding to immunotherapy. About 507 participants will be randomly assigned to receive either the combination or chemotherapy alone. The main goal is to see if the combination helps people live longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Barnes-Jewish Hospital - Siteman Cancer Center (Washington University - St. Louis)

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Carolina Oncology Specialists

    RECRUITING

    Hickory, North Carolina, 28602, United States

    Contact

  • Chan Soon-Shiong Institute for Medicine

    RECRUITING

    El Segundo, California, 90245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emory University - Winship Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Highlands Oncology Group

    RECRUITING

    Springdale, Arkansas, 72762, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Holy Cross Hospital

    RECRUITING

    Fort Lauderdale, Florida, 33308, United States

    Contact

  • Medical Oncology Associates - Summit Cancer Centers

    RECRUITING

    Spokane, Washington, 99208, United States

    Contact

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • MemorialCare - Orange Coast Medical Center

    RECRUITING

    Fountain Valley, California, 92708, United States

    Contact Email: •••••@•••••

    Contact

  • Moffit Cancer Center

    RECRUITING

    Tampa, Florida, 33612-9497, United States

    Contact

    Contact Email: •••••@•••••

  • OPN Healthcare INC

    RECRUITING

    Glendale, California, 91203, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • OPN Healthcare INC/ Cancer and Blood Specialty Clinic

    RECRUITING

    Los Alamitos, California, 90720, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tennessee Oncology

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • The Oncology Institute of Hope and Innovation

    RECRUITING

    Fort Lauderdale, Florida, 33316, United States

    Contact

    Contact Email: •••••@•••••

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Cincinnati Medical Center

    RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact Email: •••••@•••••

    Contact

  • Vanderbilt - Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Email: •••••@•••••

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23219, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.