New drug trial aims to ease debilitating muscle stiffness

NCT ID NCT06667453

Summary

This study is testing an investigational medicine called PGN-EDODM1 in adults with myotonic dystrophy type 1, a genetic disorder that causes progressive muscle weakness and stiffness. Researchers want to see if multiple doses are safe and tolerable, and if they can improve muscle function, reduce stiffness, and help with walking. The study will compare the effects of the medicine against a placebo in a small group of 24 participants.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CIUSSS du Saguenay-Lac-Saint-Jean

    RECRUITING

    Chicoutimi, Quebec, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montreal Neurological Institute

    RECRUITING

    Montreal, Quebec, H3A 2B4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Newcastle Upon Tyne Hospitals

    RECRUITING

    Newcastle upon Tyne, NE7 7DN, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ottawa Hospital Research Institute (OHRI)

    RECRUITING

    Ottawa, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pacific Clinical Research Network Auckland

    ACTIVE_NOT_RECRUITING

    Takapuna, Auckland, 0622, New Zealand

  • Salford Royal Hospital

    RECRUITING

    Salford, England, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University College London Hospitals NHS Foundation Trust

    RECRUITING

    London, UK, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 4Z6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.