New hope for easing debilitating muscle lock in rare disease

NCT ID NCT06523400

Summary

This study is testing whether a daily, extended-release version of the drug mexiletine can safely reduce muscle stiffness (myotonia) in people with myotonic dystrophy types 1 and 2. About 176 participants will take either the real drug or a placebo for 26 weeks to see if it helps them relax their grip and move more easily. The main goal is to see if the treatment improves the time it takes for hand muscles to relax after squeezing.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Denmark

  • Azienda Ospedaliera Universitaria Policlinico Tor Vergata

    RECRUITING

    Rome, Italy

  • Laboratory for Muscle Diseases and Neuropathies

    RECRUITING

    Leuven, Belgium

  • Ludug-Maximilians University

    RECRUITING

    München, Germany

  • Saint George's University Hospitals NHS Foundation Trust

    RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

  • University College Hospital

    RECRUITING

    London, United Kingdom

  • University Hospital of Madrid

    RECRUITING

    Madrid, Spain

Conditions

Explore the condition pages connected to this study.