Can special glasses or eyedrops stop kids' eyesight from getting worse?

NCT ID NCT07095894

Recruiting now Disease control Sponsor: Jaeb Center for Health Research Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two treatments to slow the progression of myopia (nearsightedness) in children aged 5 to 12. One treatment uses special glasses with tiny lenslets that may reduce eye growth, and the other uses low-dose atropine eyedrops. Over 300 children will be followed for 2 years to see if these treatments slow the worsening of their vision better than standard glasses or placebo drops.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 0.05% atropine eyedrops and spectacle lenses with highly aspherical lenslets (H.A.L.T.)
What this could lead to: If successful, this could provide a safe, non-surgical way to slow worsening nearsightedness in children, reducing the need for stronger prescriptions and lowering future eye health risks.
What could go wrong: This is a Phase 3 trial, but results from earlier studies have been mixed, especially in non-Asian children. The treatments may not work as well in this broader group, and atropine can cause side effects like light sensitivity or blurry near vision.

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Conditions

The condition(s) this trial relates to.

myopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOPIA

Contacts and locations

Locations

Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITING

Chicago, Illinois, 60611, United States
Boston Children's Hospital Waltham
RECRUITING

Boston, Massachusetts, 02453, United States
Casey Eye Institute
RECRUITING

Portland, Oregon, 97239, United States
Corewell Health
RECRUITING

Grand Rapids, Michigan, 49503, United States
Duke University Eye Center
RECRUITING

Durham, North Carolina, 27710, United States
Illinois College of Optometry
RECRUITING

Chicago, Illinois, 60616, United States
Marshall B. Ketchum University
RECRUITING

Fullerton, California, 92831, United States
Ohio State University College of Optometry
RECRUITING

Columbus, Ohio, 43210-1280, United States
Pediatric Ophthalmology Associates, Inc.
RECRUITING

Columbus, Ohio, 43205, United States
Pennsylvania College of Optometry, Salus at Drexel University
RECRUITING

Philadelphia, Pennsylvania, 19141, United States
Rocky Mountain Eye Care Associates
RECRUITING

Salt Lake City, Utah, 84107, United States
Stanford University
RECRUITING

Palo Alto, California, 94303, United States
UAB Pediatric Eye Care; Birmingham Health Care
RECRUITING

Birmingham, Alabama, 35294, United States
University of Arizona
RECRUITING

Tucson, Arizona, 85711, United States
University of Houston - College of Optometry
RECRUITING

Houston, Texas, 77204, United States
Vanderbilt University Medical Center - Vanderbilt Eye Institute
RECRUITING

Nashville, Tennessee, 37232, United States
Virginia Pediatric Eye Center
RECRUITING

Norfolk, Virginia, 23502, United States

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