Can special glasses or eyedrops stop kids' eyesight from getting worse?

NCT ID NCT07095894

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two treatments to slow the progression of myopia (nearsightedness) in children aged 5 to 12. One treatment uses special glasses with tiny lenslets that may reduce eye growth, and the other uses low-dose atropine eyedrops. Over 300 children will be followed for 2 years to see if these treatments slow the worsening of their vision better than standard glasses or placebo drops.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

0.05% atropine eyedrops and spectacle lenses with highly aspherical lenslets (H.A.L.T.)

What this could lead to

If successful, this could provide a safe, non-surgical way to slow worsening nearsightedness in children, reducing the need for stronger prescriptions and lowering future eye health risks.

What could go wrong

This is a Phase 3 trial, but results from earlier studies have been mixed, especially in non-Asian children. The treatments may not work as well in this broader group, and atropine can cause side effects like light sensitivity or blurry near vision.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Boston Children's Hospital Waltham

    RECRUITING

    Boston, Massachusetts, 02453, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Casey Eye Institute

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Corewell Health

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Eye Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Email: •••••@•••••

  • Illinois College of Optometry

    RECRUITING

    Chicago, Illinois, 60616, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marshall B. Ketchum University

    RECRUITING

    Fullerton, California, 92831, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University College of Optometry

    RECRUITING

    Columbus, Ohio, 43210-1280, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pediatric Ophthalmology Associates, Inc.

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pennsylvania College of Optometry, Salus at Drexel University

    RECRUITING

    Philadelphia, Pennsylvania, 19141, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rocky Mountain Eye Care Associates

    RECRUITING

    Salt Lake City, Utah, 84107, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University

    RECRUITING

    Palo Alto, California, 94303, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UAB Pediatric Eye Care; Birmingham Health Care

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85711, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Houston - College of Optometry

    RECRUITING

    Houston, Texas, 77204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center - Vanderbilt Eye Institute

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Virginia Pediatric Eye Center

    RECRUITING

    Norfolk, Virginia, 23502, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••