New shot may curb drooling in Parkinson's patients

NCT ID NCT00515437

First seen Apr 23, 2026 · Last updated Apr 23, 2026

Summary

This study tested whether injections of MYOBLOC (a botulinum toxin) into the saliva glands can safely reduce drooling in people with Parkinson's disease. Fifty-four participants received either the drug or a placebo, and researchers measured changes in drooling frequency and severity over 12 weeks. The goal was to find a tolerable dose that eases this bothersome symptom.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dr Hubert Fernandez

    Gainesville, Florida, 32610, United States

  • Dr Virgilio Evidente

    Scottsdale, Arizona, 85259, United States

  • Dr. Alan Freeman

    Atlanta, Georgia, 30329, United States

  • Dr. Brad Racette

    St Louis, Missouri, 63110, United States

  • Dr. Eric Molho

    Albany, New York, 12205, United States

  • Dr. Fernando Pagan

    Washington D.C., District of Columbia, 20007, United States

  • Dr. Gordon Smith

    Salt Lake City, Utah, 84132, United States

  • Dr. James Sutton

    Oxnard, California, 93030, United States

  • Dr. Joseph Friedman

    Warwick, Rhode Island, 02886, United States

  • Dr. Katie Kompoliti

    Chicago, Illinois, 60612, United States

  • Dr. Madhavi Thomas

    Dallas, Texas, 75231, United States

  • Dr. Olga Klepitskaya

    Denver, Colorado, 80262, United States

  • Dr. Patrick Hogan

    Tacoma, Washington, 98405, United States

  • Dr. Robert Rodnitzky

    Iowa City, Iowa, 52242, United States

  • Dr. Ronald Ziman

    Northridge, California, 91325, United States

  • Dr. Sam Kabbani

    Knoxville, Tennessee, 37923, United States

  • Dr. Stephen Reich

    Baltimore, Maryland, 21201, United States

  • Dr. Vanessa Hinson

    Charleston, South Carolina, 29401, United States

Conditions

Explore the condition pages connected to this study.