New shot may curb drooling in Parkinson's patients

NCT ID NCT00515437

First seen Apr 23, 2026

Summary

This study tested whether injections of MYOBLOC (a botulinum toxin) into the saliva glands can safely reduce drooling in people with Parkinson's disease. Fifty-four adults with Parkinson's and at least 3 months of drooling took part. The main goal was to see if the treatment improved drooling frequency and severity 4 weeks after the injection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DROOLING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Dr Hubert Fernandez

    Gainesville, Florida, 32610, United States

  • Dr Virgilio Evidente

    Scottsdale, Arizona, 85259, United States

  • Dr. Alan Freeman

    Atlanta, Georgia, 30329, United States

  • Dr. Brad Racette

    St Louis, Missouri, 63110, United States

  • Dr. Eric Molho

    Albany, New York, 12205, United States

  • Dr. Fernando Pagan

    Washington D.C., District of Columbia, 20007, United States

  • Dr. Gordon Smith

    Salt Lake City, Utah, 84132, United States

  • Dr. James Sutton

    Oxnard, California, 93030, United States

  • Dr. Joseph Friedman

    Warwick, Rhode Island, 02886, United States

  • Dr. Katie Kompoliti

    Chicago, Illinois, 60612, United States

  • Dr. Madhavi Thomas

    Dallas, Texas, 75231, United States

  • Dr. Olga Klepitskaya

    Denver, Colorado, 80262, United States

  • Dr. Patrick Hogan

    Tacoma, Washington, 98405, United States

  • Dr. Robert Rodnitzky

    Iowa City, Iowa, 52242, United States

  • Dr. Ronald Ziman

    Northridge, California, 91325, United States

  • Dr. Sam Kabbani

    Knoxville, Tennessee, 37923, United States

  • Dr. Stephen Reich

    Baltimore, Maryland, 21201, United States

  • Dr. Vanessa Hinson

    Charleston, South Carolina, 29401, United States

Conditions

The condition(s) this trial relates to.

Parkinson disease Sialorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.