New hope for patients battling debilitating muscle disease

NCT ID NCT06282159

Ongoing Disease control Sponsor: Dianthus Therapeutics Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug called DNTH103 in adults with generalized myasthenia gravis, a condition that causes severe muscle weakness. Researchers want to see if the drug is safe and if it helps reduce symptoms like difficulty with daily activities. The trial involves 65 participants who will receive either the drug or a placebo for 13 weeks, with an option for longer treatment.

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Contacts and locations

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Locations

Clincal Study Site

Tampa, Florida, 33620, United States
Clinical Study Site

Phoenix, Arizona, 85028, United States
Clinical Study Site

Irvine, California, 92868, United States
Clinical Study Site

Stamford, Connecticut, 06905, United States
Clinical Study Site

Boca Raton, Florida, 33487, United States
Clinical Study Site

Bradenton, Florida, 34205, United States
Clinical Study Site

Maitland, Florida, 32751, United States
Clinical Study Site

O'Fallon, Illinois, 62269, United States
Clinical Study Site

Kansas City, Kansas, 66103, United States
Clinical Study Site

Lexington, Kentucky, 40503, United States
Clinical Study Site

Boston, Massachusetts, 02215, United States
Clinical Study Site

East Lansing, Michigan, 48824, United States
Clinical Study Site

Columbia, Missouri, 65212, United States
Clinical Study Site

Cincinnati, Ohio, 45219, United States
Clinical Study Site

Columbus, Ohio, 43221, United States
Clinical Study Site

Dallas, Texas, 75206, United States
Clinical Study Site

Dallas, Texas, 75243, United States
Clinical Study Site

Houston, Texas, 77030, United States
Clinical Study Site

Lubbock, Texas, 79414, United States
Clinical Study Site

Richmond, Virginia, 23219, United States
Clinical Study Site

San Miguel de Tucumán, Tucumán Province, T4000, Argentina
Clinical Study Site

Buenos Aires, 20/11/1902, Argentina
Clinical Study Site

Buenos Aires, C1012AAR, Argentina
Clinical Study Site

Buenos Aires, C1015ABR, Argentina
Clinical Study Site

Córdoba, X5004CDT, Argentina
Clinical Study Site

Rosario, 2000, Argentina
Clinical Study Site

London, Ontario, N6A 5W9, Canada
Clinical Study Site

Ostrava, 70852, Czechia
Clinical Study Site

Copenhagen, 02100, Denmark
Clinical Study Site

Bordeaux, 33076, France
Clinical Study Site

Nice, 06001, France
Clinical Study Site

Strasbourg, 67000, France
Clinical Study Site

Haifa, 3109601, Israel
Clinical Study Site

Ramat Gan, Israel
Clinical Study Site

Safed, 13100, Israel
Clinical Study Site

Milan, 20133, Italy
Clinical Study Site

Naples, 80131, Italy
Clinical Study Site

Pisa, 56126, Italy
Clinical Study Site

Rome, 00168, Italy
Clinical Study Site

Rome, 00189, Italy
Clinical Study Site

Amsterdam, Netherlands
Clinical Study Site

Skopje, 1000, North Macedonia
Clinical Study Site

Bergen, 5021, Norway
Clinical Study Site

Bydgoszcz, 85-065, Poland
Clinical Study Site

Katowice, 40123, Poland
Clinical Study Site

Krakow, 31-202, Poland
Clinical Study Site

Krakow, 31-503, Poland
Clinical Study Site

Lublin, 20-093, Poland
Clinical Study Site

Warsaw, 01-684, Poland
Clinical Study Site

Warsaw, 02-657, Poland
Clinical Study Site

Belgrade, 11000, Serbia
Clinical Study Site

Kragujevac, 34000, Serbia
Clinical Study Site

Niš, 18000, Serbia
Clinical Study Site

Novi Sad, 21000, Serbia
Clinical Study Site

Malmo, Sweden
Clinical Study Site #2

Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.

MYASTHENIA GRAVIS, GENERALIZED