Failed trial aims to ease Drug's harsh side effects for Muscle-Weakening disease

NCT ID NCT04226170

First seen Nov 01, 2025 · Last updated Apr 11, 2026 · Updated 22 times

Summary

This study tested if adding the anti-nausea drug ondansetron could reduce stomach-related side effects like nausea and diarrhea caused by pyridostigmine, a standard medication for myasthenia gravis. It involved adults with the disease who either were experiencing these side effects or had stopped the drug because of them. The trial was terminated early after enrolling only two participants.

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Contacts and locations

Locations

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

Conditions

Explore the condition pages connected to this study.