Experimental cell therapy targets rare Muscle-Weakening disease
NCT ID NCT05451212
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times
Summary
This early-phase study tested a new cell therapy called MuSK-CAART in 7 people with a rare, severe form of myasthenia gravis caused by antibodies attacking the MuSK protein. The treatment uses the patient's own immune cells, modified to target and destroy the antibody-producing cells. The main goal was to check safety and find the right dose, with the hope of achieving long-term remission without lifelong medication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Oregon Health & Science University (OHSU)
Portland, Oregon, 97239, United States
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UC Davis, Department of Neurology
Sacramento, California, 95817, United States
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UC Irvine, Department of Neurology
Orange, California, 92868, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
Conditions
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