First-in-Human cell therapy tested for rare muscle disease

NCT ID NCT05451212

Summary

This early-stage study tested the safety of a new cell therapy called MuSK-CAART in seven people with a rare autoimmune disease that causes severe muscle weakness. Researchers gave different doses, sometimes with other medications, to see how the body handled the treatment. The goal was to find a safe dose for future studies, with the hope this therapy could lead to long-term disease remission.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Oregon Health & Science University (OHSU)

    Portland, Oregon, 97239, United States

  • UC Davis, Department of Neurology

    Sacramento, California, 95817, United States

  • UC Irvine, Department of Neurology

    Orange, California, 92868, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

Conditions

Explore the condition pages connected to this study.