New drug trial targets hardened skin in rare autoimmune disease

NCT ID NCT07287670

Summary

This study is testing an investigational drug called MTX-474 for people with diffuse cutaneous systemic sclerosis, a rare autoimmune disease that causes skin thickening and hardening. About 85 participants will be randomly assigned to receive either the drug or a placebo via an IV infusion every four weeks for 20 weeks. The main goal is to see if the drug safely reduces skin thickness and to understand how the body processes it.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • EncompaSSc site in Clearwater, FL 33765

    Clearwater, Florida, 33765, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • EncompaSSc site in Newport Beach, CA 92663

    Newport Beach, California, 92663, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.