New drug trial hopes to thicken skin Disease's fate
NCT ID NCT07287670
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called MTX-474 in 85 people with diffuse cutaneous systemic sclerosis, a condition that causes skin thickening and organ damage. Participants will receive either MTX-474 or a placebo for 24 weeks to see if the drug safely reduces skin thickness and improves disease-related gene activity. The goal is to control the disease, not cure it.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
EncompaSSc site in Baltimore, MD
RECRUITINGBaltimore, Maryland, 21224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
EncompaSSc site in Boston, MA
RECRUITINGBoston, Massachusetts, 02118, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
EncompaSSc site in Clearwater, FL 33765
RECRUITINGClearwater, Florida, 33765, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
EncompaSSc site in Dallas, TX
RECRUITINGDallas, Texas, 75246, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
EncompaSSc site in Newport Beach, CA 92663
RECRUITINGNewport Beach, California, 92663, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
EncompaSSc site in Tampa, FL
RECRUITINGTampa, Florida, 33606, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••