New drug could let EPP patients enjoy the sun longer

NCT ID NCT03520036

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study tested an experimental drug called MT-7117 in 102 adults with erythropoietic protoporphyria (EPP), a rare condition that causes severe pain from sunlight exposure. The goal was to see if the drug could increase the time people could spend in the sun without symptoms. Participants were randomly assigned to receive either the drug or a placebo, and their sun tolerance was measured over 16 weeks.

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Contacts and locations

Locations

  • ACTCA, A Member of the Alliance, Inc.

    Los Angeles, California, 90036, United States

  • Ichan School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Metro Boston Clinical Partners, LLC

    Brighton, Massachusetts, 02135, United States

  • Remington-Davis, Inc

    Columbus, Ohio, 43215, United States

  • University of California at San Francisco

    San Francisco, California, 94143, United States

  • University of Miami Miller School of Medicine

    Miami, Florida, 33136, United States

  • University of Texas Medical Branch Porphyria Center

    Galveston, Texas, 77555, United States

  • University of Utah

    Salt Lake City, Utah, 84108, United States

  • Wake Forest Baptist Medical Center

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.