New hope for tough lymphoma: experimental drug MT-2111 targets relapsed DLBCL

NCT ID NCT05658562

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 26 times

Summary

This study tests a new drug called MT-2111 for people with a type of blood cancer called diffuse large B-cell lymphoma (DLBCL) that has returned or not improved after at least two prior treatments. The first part of the study finds a safe dose, and the second part checks if the drug shrinks tumors. About 46 Japanese adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aso Iizuka Hospital

    Iizuka-shi, Fukuoka, 820-8505, Japan

  • Cancer Institute Hospital of JFCR

    Koto-ku, Tokyo, 135-0063, Japan

  • Disaster Medical Center

    Tachikawa-shi, Tokyo, 190-0014, Japan

  • Fukushima Medical University Hospital

    Fukushima, Fukushima, 960-1295, Japan

  • Gifu Municipal Hospital

    Gifu, Gifu, 500-8513, Japan

  • Gunma Prefectural Cancer Center

    Ota-shi, Gunma, 373-8550, Japan

  • Hokkaido Cancer Center

    Sapporo, Hokkaido, 003-0804, Japan

  • Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital

    Nagoya, Aichi-ken, 466-8650, Japan

  • Japanese Red Cross Nagasaki Genbaku Hospital

    Nagasaki, Nagasaki, 852-8104, Japan

  • Japanese Red Cross Society Himeji Hospital

    Himeji-shi, Hyōgo, 670-8540, Japan

  • Kanagawa Cancer Center

    Yokohama, Kanagawa, 241-8515, Japan

  • Kyushu Cancer Center

    Fukuoka, Fukuoka, 811-1395, Japan

  • Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-kofukai

    Osaka, Osaka, 530-0025, Japan

  • Nagoya Medical Center

    Nagoya, Aichi-ken, 460-0001, Japan

  • National Cancer Center Hospital

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • Osaka Saiseikai Nakatsu Hospital

    Osaka, Osaka, 530-0012, Japan

  • Shimane University Hospital

    Izumo-shi, Shimane, 693-8501, Japan

  • Shinshu University Hospital

    Matsumoto-shi, Nagano, 390-8621, Japan

  • Tohoku University Hospital

    Sendai, Miyagi, 980-8574, Japan

  • Tokyo Metropolitan Komagome Hospital

    Bunkyo-ku, Tokyo, 113-8677, Japan

  • University Hospital, Kyoto Prefectural University of Medicine

    Kyoto, Kyoto, 602-8566, Japan

  • Yamagata University Hospital

    Yamagata, Yamagata, 990-9585, Japan

Conditions

Explore the condition pages connected to this study.