MS pill challenge: can a tablet match a powerful infusion?

NCT ID NCT06846281

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is for people with relapsing multiple sclerosis (MS) who are currently getting ocrelizumab infusions. It will test if switching to a new pill called remibrutinib works as well to control the disease. About 360 participants, aged 40-70, will be randomly assigned to either switch to the pill or continue their current infusions for up to two years, followed by an option for two more years on the pill. The main goal is to see if the pill is not worse than the infusion at preventing new brain lesions seen on MRI scans.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-••••

Locations

Aqualane Clinical Research
RECRUITING

Naples, Florida, 34105, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Austin Regional Clinic
RECRUITING

Austin, Texas, 78731, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Holy Name Medical Center
RECRUITING

Teaneck, New Jersey, 07666, United States

Contact Email: •••••@•••••

Contact
John Peter Smith Hospital
RECRUITING

Fort Worth, Texas, 76104, United States

Contact

Contact Email: •••••@•••••
Lahey Hospital and Medical Center
RECRUITING

Burlington, Massachusetts, 01805, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
MedStar Montgomery Medical Center
RECRUITING

Olney, Maryland, 20832, United States

Contact

Contact Email: •••••@•••••
Medstar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010-2975, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Memorial HC Ins for Neuroscience
RECRUITING

Owosso, Michigan, 48867, United States

Contact

Contact Email: •••••@•••••
Michigan Institute of Neurological
RECRUITING

Farmington Hills, Michigan, 48334, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Neurology Associates PA
RECRUITING

Maitland, Florida, 32751, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Neurology Center of New England PC
RECRUITING

Foxborough, Massachusetts, 02035, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Neurology of Central FL Res Ctr
RECRUITING

Altamonte Springs, Florida, 32714, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Novartis Investigative Site
RECRUITING

Rosario, Santa Fe Province, 2000, Argentina
Novartis Investigative Site
RECRUITING

Rosario, Santa Fe Province, S2000BZL, Argentina
Novartis Investigative Site
RECRUITING

Buenos Aires, C1012AAR, Argentina
Novartis Investigative Site
RECRUITING

Buenos Aires, C1055AAF, Argentina
Novartis Investigative Site
RECRUITING

Melbourne, Victoria, 3004, Australia
Novartis Investigative Site
RECRUITING

Parkville, Victoria, 3050, Australia
Novartis Investigative Site
RECRUITING

Liverpool, 2170, Australia
Novartis Investigative Site
RECRUITING

St Leonards, 2065, Australia
Novartis Investigative Site
RECRUITING

Bruges, 8000, Belgium
Novartis Investigative Site
RECRUITING

Vancouver, British Columbia, V6T 2A1, Canada
Novartis Investigative Site
RECRUITING

Lévis, Quebec, G6W 0M5, Canada
Novartis Investigative Site
RECRUITING

Montreal, Quebec, H4A 3T2, Canada
Novartis Investigative Site
RECRUITING

Aarhus N, 8200, Denmark
Novartis Investigative Site
RECRUITING

Glostrup Municipality, 2600, Denmark
Novartis Investigative Site
RECRUITING

Bordeaux, 33076, France
Novartis Investigative Site
RECRUITING

Clermont-Ferrand, 63003, France
Novartis Investigative Site
RECRUITING

Lille, 59000, France
Novartis Investigative Site
RECRUITING

Marseille, 13885, France
Novartis Investigative Site
RECRUITING

Nice, 06001, France
Novartis Investigative Site
RECRUITING

Nîmes, 30029, France
Novartis Investigative Site
RECRUITING

Paris, 75940, France
Novartis Investigative Site
RECRUITING

Poitiers, 86021, France
Novartis Investigative Site
RECRUITING

Strasbourg, 67000, France
Novartis Investigative Site
RECRUITING

Toulouse, 31059, France
Novartis Investigative Site
RECRUITING

Tours, 37044, France
Novartis Investigative Site
RECRUITING

Chaïdári, 124 62, Greece
Novartis Investigative Site
RECRUITING

Larissa, 411 10, Greece
Novartis Investigative Site
RECRUITING

Thessaloniki, 53246, Greece
Novartis Investigative Site
RECRUITING

Bergamo, BG, 24127, Italy
Novartis Investigative Site
RECRUITING

Foggia, FG, 71122, Italy
Novartis Investigative Site
RECRUITING

Genova, GE, 16132, Italy
Novartis Investigative Site
RECRUITING

Milan, MI, 20132, Italy
Novartis Investigative Site
RECRUITING

Pavia, PV, 27100, Italy
Novartis Investigative Site
RECRUITING

Roma, RM, 00133, Italy
Novartis Investigative Site
RECRUITING

Roma, RM, 00168, Italy
Novartis Investigative Site
RECRUITING

Mexico City, Mexico City, 06700, Mexico
Novartis Investigative Site
RECRUITING

Mexico City, 14050, Mexico
Novartis Investigative Site
RECRUITING

Braga, 4710243, Portugal
Novartis Investigative Site
RECRUITING

Coimbra, 3004-561, Portugal
Novartis Investigative Site
RECRUITING

Lisbon, 1169-050, Portugal
Novartis Investigative Site
RECRUITING

Bratislava, 826 06, Slovakia
Novartis Investigative Site
RECRUITING

Trnava, 917 02, Slovakia
Novartis Investigative Site
RECRUITING

Cape Town, Western Cape, 7405, South Africa
Novartis Investigative Site
RECRUITING

Pretoria, 0041, South Africa
Novartis Investigative Site
RECRUITING

Majadahonda, Madrid, 28222, Spain
Novartis Investigative Site
RECRUITING

El Palmar, Murcia, 30120, Spain
Novartis Investigative Site
RECRUITING

Valencia, Valencia, 46017, Spain
Novartis Investigative Site
RECRUITING

Barcelona, 08035, Spain
Novartis Investigative Site
RECRUITING

Córdoba, 14004, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28009, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28034, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28040, Spain
Novartis Investigative Site
RECRUITING

Málaga, 29010, Spain
Novartis Investigative Site
RECRUITING

Seville, 41009, Spain
Novartis Investigative Site
RECRUITING

Valencia, 46026, Spain
Novartis Investigative Site
RECRUITING

Bern, 3010, Switzerland
Novartis Investigative Site
RECRUITING

Lausanne, 1011, Switzerland
Novartis Investigative Site
RECRUITING

Zurich, 8091, Switzerland
Novartis Investigative Site
RECRUITING

Sheffield, South Yorkshire, S10 2JF, United Kingdom
Novartis Investigative Site
RECRUITING

Swansea, SA6 6NL, United Kingdom
Ohio Health Research Institute
RECRUITING

Columbus, Ohio, 43214, United States

Contact

Contact Email: •••••@•••••
Perseverance Research Center
RECRUITING

Scottsdale, Arizona, 85253, United States

Contact Email: •••••@•••••

Contact
Premier Health
RECRUITING

Centerville, Ohio, 45459, United States

Contact Email: •••••@•••••

Contact
Premier Neurology
RECRUITING

Greenville, South Carolina, 29605, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Rush University Medical Center
RECRUITING

Chicago, Illinois, 60607, United States

Contact

Contact Email: •••••@•••••
Sanford Health
RECRUITING

Fargo, North Dakota, 58122, United States

Contact Email: •••••@•••••

Contact
Sibyl Wray MD Neurology PC
RECRUITING

Knoxville, Tennessee, 37922, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Tallahassee Neurological Clinic
RECRUITING

Tallahassee, Florida, 32308, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Univ of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Florida
RECRUITING

Gainesville, Florida, 32610, United States

Contact Email: •••••@•••••

Contact
University of Kansas Hospital
RECRUITING

Kansas City, Kansas, 66160, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of New Mexico
RECRUITING

Albuquerque, New Mexico, 87131-0001, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
WA Uni School Of Med
RECRUITING

St Louis, Missouri, 63110, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

Conditions

Explore the condition pages connected to this study.

RELAPSING MULTIPLE SCLEROSIS