New inhaled therapy for cystic fibrosis shows promise in early trial

NCT ID NCT03375047

First seen Feb 10, 2026 · Last updated May 07, 2026 · Updated 11 times

Summary

This study tested a new inhaled medicine called MRT5005 in 42 adults with cystic fibrosis. The goal was to see if it is safe and to measure how it affects lung function. The medicine was given as a mist through a nebulizer, and participants were monitored for side effects and changes in breathing. This early research helps determine if larger studies should be done.

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Contacts and locations

Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Maine Medical Center

    Portland, Maine, 04102, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • New Orleans Center for Clinical Research

    Knoxville, Tennessee, 37920, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oregon Health and Sciences University

    Portland, Oregon, 97239, United States

  • University Hospitals

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Indiana

    Indianapolis, Indiana, 46202, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.