Scientists launch Long-Term watch on rare sly syndrome

NCT ID NCT03604835

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study follows up to 50 people with MPS VII (Sly Syndrome) to learn how the disease changes over time and how well the treatment vestronidase alfa works in the long run. Researchers will track symptoms, lab results, and any side effects like allergic reactions. The goal is to better understand the disease and improve care for patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Centre Hospitalier Universitaire La Timone

    RECRUITING

    Marseille, Provence-Alpes-Côte d'Azur Region, 13005, France

  • Centro Hospitalar do Porto

    RECRUITING

    Porto, 4050-651, Portugal

  • Children's Hospital of Orange County

    RECRUITING

    Orange, California, 92868, United States

  • Children's National Health System

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

  • Erasmus University Medical Center Rotterdam

    TERMINATED

    Rotterdam, South Holland, 3015 CN, Netherlands

  • Hospital Universitario Virgen del Rocío Pabellón Infantil

    RECRUITING

    Seville, 41013, Spain

  • Hospital de Clínicas de Porto Alegre

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-003, Brazil

  • Laboratorio de Neuroquimica Dr. N.A. Chamoles S.R.L.

    RECRUITING

    Buenos Aires, C1425FNG, Argentina

  • New York University Langone Medical Center

    TERMINATED

    New York, New York, 10016, United States

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Utah Medical Center

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz

    RECRUITING

    Mainz, 55131, Germany

Conditions

Explore the condition pages connected to this study.