Gene therapy for rare childhood brain disease: tracking kids for years after treatment

NCT ID NCT04360265

Summary

This study is tracking children with Sanfilippo Syndrome A (MPS IIIA) who received an experimental gene therapy called UX111 in earlier trials. The goal is to monitor their long-term safety and see how well the treatment continues to work over many years. Researchers will check for side effects and measure brain development and disease markers. No new treatment is given in this study—it's purely for observation and data collection.

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Contacts and locations

Locations

  • Hospital Clínico Universitario de Santiago

    Santiago de Compostela, Spain

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Vall d'Hebron Barcelona Campus

    Barcelona, 08035, Spain

  • Women's and Children's Hospital

    North Adelaide, South Australia, Australia

Conditions

Explore the condition pages connected to this study.