New mpox vaccine shows promise in early trial

NCT ID NCT05988203

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This study tested a new RNA-based vaccine (BNT166a) to prevent mpox (monkeypox). About 96 healthy adults received different doses to check safety and how well the vaccine triggers an immune response. The trial is complete, and results will help decide if the vaccine should move to larger studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Addenbrooke's Hospital - Cambridge University Hospitals NHS Foundation Trust

    Cambridge, CB2 0QQ, United Kingdom

  • Alliance for Multispecialty Research, LLC

    Kansas City, Missouri, 64114, United States

  • Alliance for Multispecialty Research, LLC

    Knoxville, Tennessee, 37909, United States

  • California Research Foundation

    San Diego, California, 92123, United States

  • Guy's and St Thomas' NHS Foundation Trust of St Thomas' Hospital

    London, SE1 7EH, United Kingdom

  • Medicine Evaluation Unit Ltd, The Langley Building, Wythenshawe Hospital

    Manchester, M239QZ, United Kingdom

  • Royal Surrey County Hospital Foundation Trust, NIHR Royal Surrey Clinical Research Facility

    Guildford, GU2 7XP, United Kingdom

  • University Hospital Southampton

    Southampton, SO16 6YD, United Kingdom

  • University of Washington Virology Research Clinic

    Seattle, Washington, 98104, United States

Conditions

Explore the condition pages connected to this study.