New drug combo tested for tough blood cancers after other treatments fail

NCT ID NCT02500407

Summary

This study tested a new drug called mosunetuzumab, both alone and combined with another drug (atezolizumab), for people with B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia that had come back or stopped responding to prior treatments. The main goals were to find safe doses and see if the treatment could shrink or eliminate the cancer. It involved 713 participants and was completed.

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Contacts and locations

Locations

  • Barts Cancer Institute

    London, EC1A 7BE, United Kingdom

  • Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Complejo Asistencial Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hospital Universitario La Paz

    Madrid, 280146, Spain

  • Hospital Universitario Vall d Hebron

    Barcelona, 08035, Spain

  • Icon Cancer Care South Brisbane

    South Brisbane, Queensland, 4101, Australia

  • Jewish General Hospital

    Montreal, Quebec, H3T 1E2, Canada

  • Klinikum der Universität München, Campus Großhadern

    München, 83177, Germany

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center - Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Cancer Center at Westchester

    Harrison, New York, 10604, United States

  • Monash Health Clinical Trial Pharmacy department

    Clayton, Victoria, 3168, Australia

  • New York Uni Medical Center

    New York, New York, 10016, United States

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Princess Margaret Hospital

    Toronto, Ontario, M5G 2M9, Canada

  • Rocky Mountain Cancer Center

    Denver, Colorado, 80218, United States

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Royal Hobart Hospital

    Hobart, Tasmania, 7000, Australia

  • Royal Marsden Hospital;Institute of Cancer Research

    Sutton, SM2 5PT, United Kingdom

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Sansum Medical Clinic, Inc.

    Santa Barbara, California, 93105, United States

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • St Vincent's Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • St. Vincent's Hospital Melbourne

    Fitzroy, South Australia, 3065, Australia

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • The Perth Blood Institute

    Nedlands, Western Australia, 6009, Australia

  • Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz

    Mainz, 55101, Germany

  • Universitatsklinikum Koln

    Cologne, 50931, Germany

  • University of California San Diego Moores Cancer Center

    La Jolla, California, 92093-0698, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19103, United States

  • Universitätsklinikum Heidelberg

    Heidelberg, 69120, Germany

  • Willamette Valley Cancer Insitute and Research Center

    Springfield, Oregon, 97477, United States

  • Yale University School Of Medicine

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.