New cocktail of immune drugs shows promise against tough pancreatic cancer

NCT ID NCT03193190

First seen Nov 21, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This study tested several combinations of immunotherapy drugs in 341 people with pancreatic cancer that had spread to other parts of the body. Participants were split into two groups: those who had not yet received any treatment for their advanced cancer, and those who had already tried one type of chemotherapy. The main goal was to see if these drug combinations could shrink tumors and how safe they were. While not a cure, the approach aims to better control the disease and improve outcomes.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Columbia University

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Helen Diller Fam Comp Can Ctr

    San Francisco, California, 94158, United States

  • Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Hosp. G. U Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, 28037, Spain

  • Hospital Universitario Vall d Hebron

    Barcelona, 08035, Spain

  • Kanagawa Cancer Center

    Kanagawa, 241-8515, Japan

  • Lombardi Cancer Center, Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • MorristownMedicalCenter

    Morristown, New Jersey, 07962, United States

  • National Cancer Center Hospital

    Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Chiba, 277-8577, Japan

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Smilow Cancer Hospital at Yale New Haven

    New Haven, Connecticut, 06510, United States

  • Uni of Chicago Medical Center

    Chicago, Illinois, 60637, United States

  • Universitätsklinikum Essen

    Essen, 45122, Germany

Conditions

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