New monkeypox vaccine JT118 enters first human tests

NCT ID NCT07495202

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new vaccine called JT118 to see if it is safe and triggers an immune response against monkeypox. About 180 healthy adults aged 18 to 59 will receive either the vaccine or a placebo. Researchers will monitor for side effects and measure immune responses over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
JT118 recombinant monkeypox protein vaccine
What this could lead to
If successful, this could lead to a safe and effective vaccine to prevent monkeypox infection.
What could go wrong
This is an early Phase 1 trial with only 180 healthy adults, so safety and immune response are still unproven. The vaccine may not generate strong enough protection or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shenzhen Third People's Hospital

    RECRUITING

    Shenzhen, Guangdong, 518112, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

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