New blood test aims to spot liver cancer recurrence early

NCT ID NCT07466602

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a blood test that looks for specific gene changes (methylation of GNB4 and Riplet genes) to see if it can detect when primary liver cancer comes back after treatment. The trial will follow 500 patients who had surgery, transplant, ablation, or chemoembolization. The test's accuracy will be compared to standard clinical diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

plasma GNB4 and Riplet genes methylation detection

What this could lead to

If successful, this blood test could help doctors catch liver cancer recurrence earlier, potentially improving treatment timing and outcomes.

What could go wrong

This is a diagnostic accuracy study, not a treatment trial. The test may not be more effective than current monitoring methods, and results need validation in larger, diverse populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430030, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact