New hope for rare skin cancer: targeted antibody tested in china

NCT ID NCT06285370

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests a drug called mogamulizumab in 23 Chinese adults with mycosis fungoides or Sézary syndrome, two types of skin lymphoma that have not responded to previous treatments. The drug is given as an IV infusion and aims to shrink or eliminate cancer in the skin, lymph nodes, and blood. Researchers will measure how many patients achieve a complete or partial response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Mogamulizumab (a monoclonal antibody given by IV infusion)

What this could lead to

If successful, this could provide a new treatment option for Chinese patients with these rare skin lymphomas who have not responded to prior therapies.

What could go wrong

This is a small, single-arm study with only 23 participants, so results may not apply broadly. The drug may cause side effects and may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mycosis fungoides primary cutaneous T-cell non-Hodgkin lymphoma Sezary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • First Affiliated Hospital of Zhengzhou University

    Henan, Zhengzhou, 450052, China

  • Peking University First Hospital, Department of Dermatology and Venereology

    Beijing, Beijing Municipality, 100034, China

  • Sun Yat-sen University Cancer Center, Department of Medical Oncology

    Guangzhou, Guangdong, 510060, China

  • The Affiliated Hospital of Inner Mongolia Medical University

    Hohhot, Inner Mongolia, 010000, China

  • The First Hospital of China Medical University

    Shenyang, Liaoning, 110002, China

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610044, China

  • ZheJiang Cancer Hospital

    Hangzhou, Zhejiang, 310005, China