Engineered immune cells take on deadly skin cancer

NCT ID NCT01955460

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 26 times

Summary

This early-phase study tests whether giving patients with advanced melanoma their own genetically modified T-cells, followed by high-dose interleukin-2, is safe and feasible. The T-cells are altered in the lab to resist a protein that normally stops them from attacking tumors. About 34 adults with stage III or IV melanoma that has spread will take part. The goal is to see if this approach can shrink tumors and control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.