Bacteria vs. cancer: modified salmonella injected into tumors to starve them

NCT ID NCT05103345

First seen May 05, 2026 · Last updated May 23, 2026 · Updated 3 times

Summary

This study tests a modified salmonella bacteria (SGN1) injected directly into tumors in people with advanced solid cancers that haven't responded to standard treatments. The bacteria are designed to grow inside tumors and cut off their food supply (an amino acid called methionine), potentially shrinking or controlling the cancer. The main goals are to check safety, find the best dose, and see if it helps control the disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China Medical University Hospital

    RECRUITING

    Taichung, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangdong Clifford Hospital

    RECRUITING

    Guangzhou, Guangdong, 511495, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare

    RECRUITING

    New Taipei City, 23561, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.