Gene clues could predict root canal success
NCT ID NCT07529964
First seen Apr 15, 2026 · Last updated Jun 23, 2026 · Updated 13 times
Summary
This study will check if certain gene variations (MMP-2 and MMP-3) are linked to how well the bone heals after a root canal. Fifty adults with chronic tooth infections will get standard root canal treatment and be followed for 12 months. Researchers will compare healing in people with different gene types to see if genetics play a role.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help dentists predict which patients might heal better after root canal treatment based on their genes.
What could go wrong
This is a small, early-stage study (50 people) that only looks at genetic links, not a treatment. It may not find a clear connection or lead to any change in practice.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.