Can a nanoparticle deliver chemo more safely to Hard-to-Treat cancers?

NCT ID NCT07723482

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial is testing an experimental drug called ML-016, a nanoparticle form of the chemotherapy doxorubicin, in people with advanced solid tumors that have spread to the lungs or liver. The study aims to find the safest dose and see whether the drug can shrink tumors or slow their growth. Participants must have cancers that no longer respond to standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a nanoparticle form of the chemotherapy drug doxorubicin, designed to target tumors more precisely
What this could lead to
If it works, this could offer a new treatment option for people with advanced cancers that have spread to the lungs or liver and have stopped responding to standard therapies.
What could go wrong
This is an early-phase trial, so the drug may not work as hoped or could cause serious side effects. The nanoparticle design is new, so its safety and effectiveness are still unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm Neoplasm Metastasis Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Illawarra Cancer Care Center, Wollongong Hospital

    Wollongong, New South Wales, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Southside Cancer Care Centre

    Miranda, New South Wales, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sunshine Coast Haematology and Oncology Clinic

    Buderim, Queensland, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••