New schizophrenia drug passes early safety check in small study

NCT ID NCT04506905

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called MK-8189 (elpipodect) in 63 people with schizophrenia, including both younger and older adults, as well as healthy older volunteers. The main goal was to check the drug's safety and how the body processes it, not to cure the disease. Results will help decide if larger studies should move forward.

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Conditions

The condition(s) this trial relates to.

schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Collaborative NeuroScience Network ( Site 0008)

    Long Beach, California, 90806, United States

  • Hassman Research Institute ( Site 0007)

    Berlin, New Jersey, 08009, United States

  • Parexel ( Site 0004)

    Glendale, California, 91206, United States

  • RCA at Fort Lauderdale Behavioral Health Center ( Site 0006)

    Oakland Park, Florida, 33334, United States

  • Velocity Clinical Research, Hallandale Beach ( Site 0001)

    Hallandale, Florida, 33009, United States

  • Woodland Research Northwest, LLC ( Site 0002)

    Rogers, Arkansas, 72758-6442, United States